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Research

  • 2012 - TIPS 3 – Principal Investigator

    A randomized double-blind placebo-controlled trial for evaluation of a polycap, low dose aspirin and vitamin D supplementation in primary prevention-The International Polycap study 3 (TIPS 3) Sponsors - Cadila Pharmaceuticals Limited , Wellcome Trust

  • 2016 – REVERSAL OF DIABETES and OBESITY PROGRAM

    A lifestyle modification program undertaken by Belgaum Diabetes Centre to reverse or remit type 2 diabetes and obesity.

Research Past

  • PRINCIPAL INVESTIGATOR from the year 2006, for more than 45 global clinical trials spanning Phase 1 to Phase 4, in diabetes, obesity, cardiac prevention trials and diabetic foot, some of which are listed below in the published articles, in the Collaborator List. Some of the recently completed trials are:

  • HOPE 3 – Principal Investigator

    A large, simple multicentre, international randomized placebo-controlled trial utilizing a 2 x 2 factorial design and evaluating cholesterol modification with rosuvastatin vs. placebo, blood pressure lowering with candesartan/HCT vs. placebo and combined treatment with rosuvastatin and candesartan/HCT vs. placebo on major vascular events Acronym: HOPE-3 (Heart Outcomes Prevention Evaluation. Currently in the phase of passive follow up.

    Sponsor - Population Health Research Institute, McMaster University Hamilton General Hospital237,Barton St

  • CAROLINA - Principal Investigator. Recently completed

    A multicentre, international, randomised, parallel group, double blind study to evaluate Cardiovascular safety of linagliptin versus glimepiride in patients with Type 2 Diabetes Mellitus at high cardiovascular risk."

    Sponsor - Boehringer Ingelheim Pharmaceuticals

  • CANVAS – Principal Investigator

    A Randomized, global, multicenter, Double-Blind, Parallel, placebo-Controlled Study to evaluate the Effects of JNJ- 28431754 on Cardiovascular Outcomes in Adult Subjects With Type 2 Diabetes Mellitus.

    Sponsor – Johnson and Johnson

Publications - Journals

  • Diabetes in Pregnancy, Neeta Deshpande, Journal of South Asian Federation of Obstetrics and Gynaecology 2010, Vol 2, Number 1, Pages 1-5

  • Hypoglycemia in type 2 diabetes: Standpoint of an experts' committee (India hypoglycemia study group) Indian J Endocrinol Metab.Year : 2012 | Volume : 16 | Issue : 6 | Page : 894-898 Mohan Viswanathan1, Shashank R Joshi2, Anil Bhansali3, Mohan Badgandi4, Subhankar Chowdhury5, Neeta Deshpande6, Shreerang Godbole7, K Kannan8, Surender Kumar9, RV Jayakumar10, Tiny Nair11, Prashant Narang12, Anant =Nigam13=, Mihir Saikia14=, Bipin Sethi15=, MA Shekar16=, Vikram=, SS Srikanta17=, KK -Tripathi18-, Vijay Viswanathan19-, SK Wangnoo20

  • Eight cases of bladder cancer in pioglitazone users from India. Unnikrishnan R, Sundramoorthy C, Deshpande N, Sarvothaman R, Sahay RK, Mehtalia S, Venkatraman JV, Mohan V. J Assoc Physicians India. 2012 Dec;60:66.

  • Clinical experience with insulin detemir, biphasic insulin aspart and insulin aspart in people with type 2 diabetes: Results from the Karnataka cohort of the A1chieve study.
    Indian J Endocrinol Metab. 2013 Nov;17(Suppl 2):S552-6. doi: 10.4103/2230-8210.122132. Deshpande N1, Ayyar V2, Channabasavaiah R3, Shetty R3, Behl A4.

  • Weight adds weight to declining quality of life in diabetes. Aravind SR1, Deshpande N. Curr Med Res Opin. 2014 Jul;30(7):1275-8. doi: 10.1185/03007995.2014.901944. Epub 2014 Mar 26.

  • Phenotypic severity of homozygous GCK mutations causing neonatal or childhood-onset diabetes is primarily mediated through effects on protein stability. Raimondo A1, Chakera AJ2, Thomsen SK1, Colclough K3, Barrett A1, De Franco E4, Chatelas A1, =Demirbilek H5=, Akcay T6=, Alawneh H7=; The International NDM Consortium, Flanagan SE4=, -Van De Bunt M1-, Hattersley AT2-, Gloyn AL8-, Ellard S9-; The International NDM Consortium. Collaborators (22) Abduljabbar MA, Al-Zyoud M, Aman S, Bath L, De P, Deshpande N, Durmaz E, Eickmeier F, Elbarbary NS, Fillion M, Jagadeesh SM, Kershaw-M, Khan WI, Mlynarski W, Noyes K, Peters CJ, Shaw N, Tiron I, Turkkahraman D, Turner-L, Eltonbary KY, Yuksel B. Hum Mol Genet. 2014 Dec 15;23(24):6432-40

  • Madhu S V, Saboo B, Makkar M B, Reddy G C, Jana J, Panda J K, Singh J, Shetty N, Rao PV, Chawla R, Sahay R K, Sosale A, Banarjee S, Bajaj S, Kumar V, Panikar V,Munichoodappa C, Mohan V, Kumar K M P, Ayyer V, Unnikrishnan R, Reddy S, Sosale B, Mohan A, Chowdary S, Tandon N, Ramachandran A, Bachani D, Aggarwal A, Misra A, Vikram N, Ghosh S, Deshpande N, Sharma J K, Das A K, Sahay B K, Bantwal G, Unnikrishnan A G, Rao S, Joshi S,Vishwanathan V, Bhoraskar A, Negalur V, Chopra V, =Gupta A, Aggarwal S, Sheshadri K, Dharmalingam M, Sanyal D, Mittal V, Vidyasagar S, Singh S K, Jaggi S, Das S, Kalra S, Julka S, Gupta Y, Punyani H on behalf of the Guideline Development Group. RSSDI Clinical Practice Recommendations for Management of Type 2 Diabetes Mellitus, 2015, Int J Diabetes Dev Ctries Oct 2015;35:S1-S71.

  • A Multicenter Real-Life Study on the Effect of Flash Glucose Monitoring on Glycemic Control in Patients with Type 1 and Type 2 Diabetes. Ranjit Mohan Anjana, MD, PhD, 1  Jothydev Kesavadev, MD, 2  Deshpande Neeta, MD, 3  Mangesh Tiwaskar, MD, 4  Rajendra Pradeepa, MSc, PhD, 1,2  Saravanan Jebarani, EMBA, 1  Suresh Thangamani, MSc, 1  Nadiminty Ganapathi Sastry, MBBS, Dip.Diab, 1  Srivastava Brijendra Kumar, MBBS, F.Diab, 1  Muthu Ramu, MD, F.Diab, 1  Pokal Prasanna Kumar Gupta, MBBS, F.Diab, 1  Jayaprakash Vignesh, MBBS, F.Diab, 1 Sundramoorthy Chandru, MBBS, F.Diab, 1  Sengottuvel Kayalvizhi, MBBS, F.Diab, 1  Padoor Sethuraman Jagdish, MBBS, F.Diab, 1  Subash Chandra Bose Uthra, MBBS, F.Diab, 1  Munawar Lovelena, MBBS, F.Diab, 1  Sah Jyoti, MD, 1  Sengodan Suguna Priya, MBBS, DFM, 1  Alagarsamy Kannan, MBBS, F.Diab, 1  Viswanathan Mohan, MD, DSc, 1  and Ranjit Unnikrishnan, MD 1 Diabetes Technology & Therapeutics. September 2017, Vol. 19, No. 9: 533-540

Publications – Book Chapters

  • 2000

    Hyper Androgenism in Adolescence in “Adolescence- Obstetrics and Gynaecology in Perspective” published by Orient Longman

  • 2003

    Pathogenesis of Insulin Resistance-Newer Concepts in “Newer Horizons in type 2diabetes”

  • 2004

    Problems of Diabetes Care In Rural Patients –Do We Have The Solutions? In “Type 2 diabetes – Urban-Rural”

  • 2005

    Patient Education in Type 2 Diabetes in “Type 2 Diabetes in Elderly”.

  • 2006

    - Insulin Resistance And Dyslipidemia in “Type 2 Diabetes and The Role of Insulin Resistance”

  • 2010

    Prediabetes:To Treat or Not? In “Controversies in Type 2 Diabetes”

  • 2016

    Glucagon like peptide 1 Analogs for Obesity Management in “RSSDI Diabetes Update 2016”

  • Appointed as Section Editor (Section on Diabesity) “Sadikot’s Textbook of Diabetes” to be released in December 2017. Book released at IDF

  • Contributed chapter titled “Malignancy and Diabetes” to the RSSDI Textbook of diabetes.

  • Chapter in RSSDI Diabetes Update 2018 “Obesity Management:Surgical knife or Drugs and Lifestyle?”

  • Chapter in API Update 2019 “Reversal of Diabetes”